Impact R Laboratory platelet function cone and plate analyser
July 28th, 2011
Impact R Workstation
The laminar flow over the polystyrene surface of the well is achieved according to the cone and plate principal. The device can also give indication for patient response to drugs such as Aspirin or Plavix®.
Upon application of a blood sample (130 u l) into the polystyrene well, plasma proteins immediately adhere to the well surface and attract for platelets, resulting in platelet adhesion and aggregation on the well surface under flow conditions. Following removal by washing of the excess blood and staining of adhered platelets, a count of the results is performed by an image analyzer.
The results are expressed as the percentage of the well surface covered by platelets aggregates (percentage SC) representing platelet adhesion and the average size of the aggregates (AS in u m2) representing platelet aggregation.
The Impact-R (cat. no. 866004V) can also be used for the study of platelet function, screening of primary hemostasis abnormalities including thrombocytopenia and monitoring their therapies. It can be used for testing both hypo- and hyper-function of platelets. Furthermore, it provides a quick method for monitoring the response to various anti platelet drugs.
