Impact R Laboratory platelet function cone and plate analyser

Impact R workstation setup

Impact R Workstation

The laminar flow over the polystyrene surface of the well is achieved according to the cone and plate principal. The device can also give indication for patient response to drugs such as Aspirin or Plavix®.

Upon application of a blood sample (130 u l) into the polystyrene well, plasma proteins immediately adhere to the well surface and attract for platelets, resulting in platelet adhesion and aggregation on the well surface under flow conditions. Following removal by washing of the excess blood and staining of adhered platelets, a count of the results is performed by an image analyzer.

The results are expressed as the percentage of the well surface covered by platelets aggregates (percentage SC) representing platelet adhesion and the average size of the aggregates (AS in u m2) representing platelet aggregation.

The Impact-R (cat. no. 866004V) can also be used for the study of platelet function, screening of primary hemostasis abnormalities including thrombocytopenia and monitoring their therapies. It can be used for testing both hypo- and hyper-function of platelets. Furthermore, it provides a quick method for monitoring the response to various anti platelet drugs.


2 Responses to “Impact R Laboratory platelet function cone and plate analyser”

  1. Effect of Statins on Platelets | Impact-R Resource Center Says:

    [...] which examined the effects of statins on platelet adhesion and aggregation. This study utilized the IMPACT-R to determine aggregate size and surface coverage of platelets taken from hypercholesterolemic and [...]

  2. Aspirin use in Diabetes mellitus II | Impact-R Resource Center Says:

    [...] high-risk DM II patients. The laboratory parameters used were impedance aggregometry (WBA) and the IMPACT-R (CPA). An abstract of the study can be found [...]

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